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Alzheimer's disease is a progressive, degenerative disorder that attacks the brain's nerve cells, or neurons, resulting in loss of memory, thinking and language skills, and behavioral changes.

These neurons, which produce the brain chemical, or neurotransmitter, acetylcholine, break connections with other nerve cells and ultimately die. For example, short-term memory fails when Alzheimer's disease first destroys nerve cells in the hippocampus, and language skills and judgment decline when neurons die in the cerebral cortex.(source)

Do you or a loved one have..

What does it mean?

    The SERENE clinical research study is looking for people with Alzheimer's disease who have agitated and aggressive behaviour.

How long is the study?

    If you volunteer and qualify for this study, your loved one will receive study medication for up to 12-weeks. During the study they will be asked to make regular visits to the clinic. His or her health is very important to us, and will be monitored throughout the study.

How to participate?

    Please take your time to make your decision about taking part. You may discuss your decision with your friends and family. You can also discuss it with your health care team. If you have any questions, you can ask your study doctor for more explanation.

You must be..

  • Age 50 or older
  • Diagonosed with Alzheimer's Disease
  • Showing agitated and aggressive behavior
  • Active disease
  • Willingness and ability to comply with trial and follow-up procedures, give written consent
  • You can't be..

  • The agitation/aggression is attributable to concomitant medications, environmental conditions, substance abuse, or active medical or psychiatric condition
  • Has a current major depressive disorder episode (within 3 months) according to the Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition (DSM-5) criteria
  • Subject or study partner/caregiver has a medical condition (e.g., hearing, vision impairments) that would impair the ability to perform the study assessments.
  • Qualified volunteers will recieve

  • No-cost study medication for agitation/agression in patients with Alzheimer's Disease
  • No-cost-study-related medical care
  • Reimbursement for time and travel

    if you are interested or someone you know that might be eligible, fill out our survey form here